The Brazilian, who hopes to be fully fit to face the Premier League side, believes the Catalan club's extra European experience will be key in the Champions League last 16 tie
City spent upwards of a 100 million pounds in the summer on new players. The influx helped ensure qualification for the knockout stages of the Champions League for the first time after two embarrassing early exits under Roberto Mancini.
If Manuel Pellegrini’s side is to progress further in the competition, it will have to overcome a Barcelona side whose recent pedigree in Europe’s premier club competition is unrivaled.
City has won admirers this season for its attacking prowess, with over 100 goals in all competitions, but Neymar believes a lack of European experience will be the Manchester side's downfall against Barcelona.
He told Goal: “I have read the things about Manchester City beating Barcelona because of the amount of goals they are scoring in England - but I think the reality is that Manchester City are still a long way behind Barcelona.
“They do have very good players - but we have much more experience in the competition.
“We will respect them - but if we concentrate and play the way we know we can - then I think we will progress.”
Neymar returned to full training last week and scored in Saturday's 6-0 drubbing of Rayo Vallecano having recovered from an ankle injury that has kept him out of action since early January, and is hopeful of being fit enough to have a significant impact on the tie.
He added: “Of course I am desperate to be back for the games against Manchester City. This was why I chose to play for Barcelona - so I could be involved in important European nights like this.
“Every competition is important for us - but of course there is something very special about the Champions League - and it is my dream to win it this season.”