The former Valencia coach took over at Luzhniki Stadium in May, but after a 5-1 loss at the hands of rival Dinamo Moscow, Emery has been relieved of his duties.
The former Valencia boss has not had the best of times at the capital club, which currently sits in sixth place in the Premier League after 17 games, outside the European places.
Spartak suffered a 3-0 home defeat to Barcelona this past week, leaving the club in fourth place in its UEFA Champions League group and eliminated from European competition. That was followed up with a crushing 5-1 loss to local rivals Dinamo Moscow on Sunday, and general director Valery Karpin confirmed Emery's dismissal at the post-match press conference.
"I have one announcement. It has been decided by shareholders of the club that Emery will no longer coach Spartak," Karpin said. "What happens next will all be announced tomorrow [Monday] or the day after."
When Karpin, who coached Spartak for the previous three years, was questioned on whether he would take control of the team once more, he simply replied, "No idea."