The 29-year-old will spend some time on the sidelines after sustaining a calf problem and could miss the club's next five matches
A scan on Wednesday evening revealed an injury to soleus muscle of his calf, a problem that could see him miss up to a month of action, according to Genovatoday.it.
Gilardino is expected to miss the club's Serie A matches against Catania, Atalanta, Chievo, Parma and Lecce.
The news comes as a blow to the former Fiorentina striker, who signed for Genoa in the winter transfer window.
The Italian has scored one goal in five Serie A appearances for Genoa.