The world champion put Italy to the sword in Kiev a year ago with a resounding 4-0 win in the European championship final, and Del Bosque has warned his players to expect an attempted retaliation from Cesare Prandelli's men.
"For Italy, the semifinals will serve as a revenge," Del Bosque told Tele Cinco. "They will be a very difficult opponent, they're one of the best teams in Europe and the world.
"It's going to be a rematch for them, but we want to proceed [to the final]."
Spain will lock horns with Italy in Fortaleza on Thursday, 24 hours after host Brazil takes on Uruguay in the first semifinal of the tournament.