Host nation Brazil has already been joined by Asian representatives Japan, Australia, Iran and South Korea, European giants Netherlands and Italy, as well as USA, Costa Rica and Argentina.
Additionally, a number of nations from Africa, Europe, North America and South America can also seal qualification in the upcoming days.
In Group A of the UEFA qualifying campaign, Belgium is sitting in pole position to qualify for the 2014 World Cup, as a draw away against Croatia on Friday will be enough to see Marc Wilmots' star-studded squad through.
Elsewhere, Germany can secure the top spot in Group C with a win over Republic of Ireland, while even a draw or a loss will suffice if second-placed Sweden fail to beat Austria.
In Group E, Switzerland is on the verge of qualifying for next year's competition, as a win over Albania would clinch top spot in its section. A draw could be enough for Ottmar Hitzfeld's man as well, but only if Iceland drops points against Cyprus, while defeat will only see it through if both Iceland and Slovenia fail to win.
Russia is the sole team from Group F that can qualify on Friday, but it will have to beat Luxembourg, while second-placed Portugal will have to lose against Israel in order for Fabio Capello and his men to seal their berth in Brazil.
Bosnia-Herzegovina will qualify for the World Cup from Group G if it beats Liechtenstein on Friday and Greece is beaten by Slovakia in Piraeus.
Finally, in Group I, reigning world champion Spain will seal the deal with a win over Belarus at Palma de Mallorca on Friday.
In South America, Colombia can wrap up qualification on Friday if it bags at least one point against Chile on Friday, while even a loss will do the trick if the game between Uruguay and Ecuador does not end in a draw.
Chile, meanwhile, will qualify with a win over the Colombians. Furthermore, the winner of the game between Uruguay and Ecuador in Quito will advance, too.
In CONCACAF, Honduras can become the third team to qualify if it beats Costa Rica on Friday and Panama fails to beat Mexico.
Finally, this weekend also marks the first legs of the African playoffs, with Burkina Faso hosting Algeria, Cote d'Ivoire taking on Senegal, Ethiopia versus Nigeria, Tunisia against Cameroon and Ghana locking horns with Egypt.
Oceania representative New Zealand and Asian side Jordan will be closely monitoring the action in North- and South-America respectively, with the Intercontinental play-offs taking place in November.
|NATIONS ALREADY QUALIFIED FOR 2014 WORLD CUP
|TEAM||CONFEDERATION||LAST APPEARANCE||BEST PERFORMANCE|
|Japan||AFC||2010||Round of 16|
|Australia||AFC||2010||Round of 16|
|South Korea||AFC||2010||Fourth place|
|Costa Rica||CONCACAF||2006||Round of 16|