The Blaugrana boss believes the English giants will not be happy about being drawn against his side in the last 16 of the Champions League.
The Premier League club has been unstoppable on home turf all season, winning all eight of its domestic matches and scoring a total of 16 goals against Manchester United, Arsenal and Tottenham. Martino will take his side to the Etihad Stadium for the first leg of the tie in February.
"There were six outcomes and we drew Manchester City," Martino told reporters. "You've got to play whoever you get but they will not want to play against Barcelona. They are important opponents with very good players, but we will go there to win. The most important thing is to arrive at their stadium in good shape and play well."
And Martino also said he was looking forward to pitting his managerial wits against former Real Madrid coach Manuel Pellegrini.
"It will be very interesting to have a game against a Pellegrini side as I think he is one of the best coaches in the world," he said.