Ahead of Manchester United's last-16 first leg clash with the Spanish giant, the Scottish boss has claimed that Jose Mourinho's side has written off La Liga success.
The two sides are set to go head to head at the Santiago Bernabeu in the first leg of their last-16 tie on Wednesday evening.
"I think their target is the European Cup. They got a bad start in the league and were chasing their tail a bit because Barcelona's form has been incredible," Ferguson said.
Los Blancos are currently 16 points shy of Liga leader Barcelona in Spain, and Ferguson expects Jose Mourinho's men to be fully committed to earning the right result.
" I think Jose has set his targets firmly on the European Cup, no doubt about that. It can be harder for us but there's a bit of pressure for them too," Ferguson added.
"At this moment in time we're involved in three things. Jose has still got the semifinal of the Copa del Rey, they play Barca next week and then again in a league game before we play them on the Tuesday at Old Trafford. So they've got a big program themselves."