The veteran midfielder looks back at the last time the Red Devils came up against their Turkish opponents.
The 38-year-old featured the last time these two sides met in the second knockout round in Istanbul in 1993. The Red Devils needed a victory to go through, after a 3-3 draw in the first leg at Old Trafford, but could only achieve a goalless draw at the Ali Sami Yen Stadium.
The experienced midfielder remembers the hostile environment the team encountered when it landed in Turkey, and the aggressive nature of the fans, and expects a similar experience on Wednesday night.
"I remember it vividly. It will always stick with me," Giggs told reporters. "I was 19 and, when we arrived at the airport, there were all the banners and fans. Thousands of fans screaming at you.
"There were things being thrown at us when we were driving away on the coach. Outside the hotel their fans were chanting all night, making sure we didn't get any sleep. People were phoning the hotel room."
Prior to the game, Giggs said fans had been at the stadium for hours prior to kickoff.
"There were armed police either side - not the kind of people you would ever mess with. They had helmets, batons, were all ready. And it just kicked off," he added. "I was just trying to get back to the safety of the dressing room as quickly as possible."
The veteran midfielder made his 600th league appearance for Manchester United over the weekend.