Sydney Leroux made sure the national team didn't miss a beat with Alex Morgan sidelined by a knee injury.
The striker notched four goals in the first half, Abby Wambach, Rachel Buehler and Morgan Brian added tallies of their own, and the United States defeated Mexico 7-0 before 12,594 at RFK Stadium.
Ten minutes after Wambach opened the scoring in the 11th minute with her 161st international goal, Leroux got on the board by nodding home the rebound of a Wambach shot.
Just one minute later, Leroux grabbed her second when she tapped in a shot from Lauren Holiday that had been slowed by goalkeeper Cecilia Santiago.
Leroux made it a hat trick within the span of nine minutes when she darted into the box, fended off a challenge and hit an off-balance shot that trickled in. And four minutes before intermission, Leroux capped the half by heading in a free kick from Holiday.
Although Leroux was held off the board in the second half, substitutes Buehler and Brian both bagged goals moments after entering to further run up the score. It was the first international goal for Brian, a junior at the nearby University of Virginia.
Morgan dressed for the match but sat out with a knee injury as a precaution.