The Honduran squad continued to roll from their excellent previous match versus Costa Rica.
The scoring started fast and furiously in San Pedro Sula, as ex-Galaxy player Carlos Pavon put goals in in the 19th and 27th minutes. Toronto FC's Amado Guevara scored in the 61st.
Inter's David Sauzo, who also had multiple assists on the day, notched for himself in the 82nd minute.
Trinidad and Tobago managed a late consolation goal when Kerry Baptiste scored in the 85th for Trinidad and Tobago.
Both teams came into the match with wins in their previous games. Honduras had their confidence-building 4-0 victory over Costa Rica on August 12 and Trinidad and Tobago defeated El Salvador 1-0 on the same date.
Only three teams from CONCACAF advance directly to the World Cup finals. The fourth-placed team plays off for a berth against the fifth-placed team from South America.
The victory gave Honduras thirteen points, level with the United States, while Mexico and Costa Rica are tied at twelve. Honduras and Mexico are placed ahead in the standings on goal difference.
Trinidad and Tobago and El Salvador both have five points.