Expansion sides Portland and Vancouver have first fixture unveiled.
The 18 teams in the league will play a balanced 34-match schedule with everyone playing each other once in a home and away fixture.
The Vancouver Whitecaps will open their inaugural campaign against Toronto FC on March 19th while the Porland Timbers will have to wait until April 14th before their stadium opens.
Sporting KC will open their new stadium in June which means the opening part of their schedule will be heavy with away fixtures.
A full list of the home openers can be seen below.
Tuesday, March 15
Seattle Sounders FC vs. LA Galaxy, 9:30 p.m. (ESPN, ESPN Deportes, ESPN3.com)
Saturday, March 19
Vancouver Whitecaps FC vs. Toronto FC, time TBD
D.C. United vs. Columbus Crew, 7:30 p.m.
New York Red Bulls vs. Seattle Sounders FC, 7:30 p.m.
FC Dallas vs. Chicago Fire, 8:30 p.m.
Houston Dynamo vs. Philadelphia Union, 8:30 p.m.
Colorado Rapids vs. Portland Timbers, 9 p.m.
Chivas USA vs. Sporting Kansas City, 10:30 p.m.
San Jose Earthquakes vs. Real Salt Lake, 10:30 p.m.
Sunday, March 20
LA Galaxy vs. New England Revolution, 8 p.m.
Saturday, March 26
Chicago Fire vs. Sporting Kansas City, 4 p.m.
Columbus Crew vs. New York Red Bulls, 4 p.m.
Philadelphia Union vs. Vancouver Whitecaps FC, 4 p.m.
Toronto FC vs. Portland Timbers, time TBD
New England Revolution vs. D.C. United, time TBD
Real Salt Lake vs. LA Galaxy, 9 p.m.
Thursday, April 14
Portland Timbers vs. Chicago Fire, 11 p.m.
Thursday, June 9
Sporting Kansas City vs. Chicago Fire, time TBD
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