Michael Laudrup's side has not won a Premier League game since December 4 and faces a Spurs outfit which is unbeaten in the top flight since the appointment of Tim Sherwood.
The dismal streak, broken up somewhat by a memorable 2-1 FA Cup victory over Manchester United at Old Trafford two weeks ago, sees Michael Laudrup's men sit just three points clear of the Premier League relegation zone.
A Crystal Palace win Saturday adds pressure on Swansea to get a result at the Liberty Stadium - and recent history does not read in the Swans' favor.
Tottenham came away with a 1-0 victory from the reverse fixture in August, and Swansea's last league win against the north London outfit was way back in 1982. The Swans did, though, record a League Cup victory over Tottenham at the Vetch Field in 1991.
This weekend's visitors have been in a rich vein of form recently and are unbeaten in the Premier League under new head coach Tim Sherwood.
The White Hart Lane club has won four of those games and currently sits eleven points adrift of leaders and local rivals Arsenal after the Gunners' win against Fulham on Saturday.
Laudrup could welcome Michel Vorm [knee], Roland Lamah [abductor] and Dwight Tiendalli [hamstring] back to the fold for the visit of Tottenham but, while wingers Nathan Dyer [ankle] and Pablo Hernandez [hamstring] have returned to full training for the hosts, they are unlikely to be ready in time to play.
Jose Canas [ankle] and Jonathan de Guzman [calf] will both miss out, as Swansea looks to cope with a midfield injury crisis not helped by Michu's [ankle] continued absence.
Former Swansea midfielder Gylfi Sigurdsson [calf] is back in contention for Tottenham, while Andros Townsend [hamstring] could make his return after scoring for the Under-21s in midweek.
Jan Vertonghen [ankle] and Younes Kaboul [thigh] have resumed training but will not feature on Sunday, while Paulinho [ankle] remains sidelined.