Swan's magnificent home start to Premier League life continues with a win over Pulis' Potters thanks to a first half penalty from Sinclair and Danny Graham's first for the club.
The game was a scrappy affair on the whole with referee Mike Jones booking eight players.
Swansea started brightly as it passed its way around the field and took the lead inside the first 10 minutes.
Joe Allen surged through midfield and looked to play Swans debutant Wayne Routledge into the box where he beat Shawcross to the ball. The Stoke captain only managed to trip Routledge and concede a spot kick which Sinclair tucked away.
It had been nothing more than the Swans deserved for their bright start and it seemed to shock Stoke into life. The visiting side had a chance to equalize through a Pennant free-kick but the former Liverpool winger could only hit the wall.
The Potters came close to equalizing again on 20 minutes as Walters picked up the ball in midfield and unleashed an effort which Michel Vorm did magnificently well to tip onto the crossbar.
Stoke's challenge fizzled out as the half went on, with the only remaining chance seeing Rory Delap fire high and wide from 20 yards.
In the second frame Tony Pulis' side was still looking for an equalizer and came as close as it had through Glenn Whelan as he hit the post with a free-kick.
The Swans then finally managed to wrap up the game, Glenn Whelan gave the ball away in midfield to Allen who played it to Graham. Jonathan Woodgate was weak in the challenge with his former Middlesbrough teammate and when one on one with Begovic, Graham showed great composure to stroke the ball home for his first goal since signing with the club.
Peter Crouch had a late chance to grab a consolation goal but Vorm saved well to preserve his record of not having conceded a home goal so far this season as Swansea celebrated a well earned win.