The home side snapped a poor run of form against a poor Toffee squad on Saturday.
Southampton ended its poor run of Premier League form by overcoming a lackluster Everton side 3-0 at St Mary's Stadium on Saturday.
A Romelu Lukaku own-goal combined with second-half goals from Graziano Pelle and Maya Yoshida ensured that Ronald Koeman's men secured their first victory in five league outings.
Everton was beaten 2-0 in the corresponding fixture last season thanks to two own-goals and that trend continued when Lukaku put through his own net in the 38th minute.
Pelle missed a gilt-edged chance to double the advantage soon after, but the out-of-sorts forward made amends 20 minutes into the second half when he prodded in his second goal in his last nine league appearances.
Roberto Martinez's men showed no real conviction as they attempted to pull one back and Yoshida's 82nd-minute header condemned Everton to its sixth Premier League loss of the campaign.
Southampton was without several key players, with Koeman employing a back three to compensate for the loss of Morgan Schneiderlin and Victor Wanyama in midfield.
Everton, which made two changes from the team that beat QPR on Monday, retained possession well in the early stages, but Southampton looked dangerous on the counter and was controversially denied a free kick after Sylvain Distin felled Shane Long just outside the area.
Referee Jon Moss was at the center of controversy once again when Long was brought down in mid-air by Phil Jagielka after the forward latched onto Steven Naismith's wayward touch, but the penalty claims were waved away.
A corner was awarded instead, despite the last touch coming off Long, but Southampton will feel that justice was done when James-Ward Prowse's cross resulted in Lukaku heading into his own net under pressure from Jose Fonte.
Southampton almost snatched a second two minutes later as Ryan Bertrand drove down the left before drilling in a low cross to Pelle, but the Italian could only fire into the side-netting from close range.
Ross Barkley impressed in a deep-lying central role in Everton's win over QPR last time out, but the midfielder struggled to make an impact operating on the left flank as the visitors pushed for an equalizer.
Everton stepped up the intensity as the hour mark approached, but Southampton's back-line stayed strong, with the hosts content to play on the break.
And it was Southampton which increased its lead when Pelle latched onto Long's knock-down to poke through the legs of Tim Howard.
The American goalkeeper did manage to prevent Pelle grabbing a second immediately after, diving down low to his left to parry away the striker's header.
Fraser Forster was finally called into action at the other end after 73 minutes when he reacted well to parry away Lukaku's dipping long-range strike.
Matters were made worse for the visitors when Yoshida latched onto Steven Davies' cross to head past Howard and put the result beyond all doubt with just under 10 minutes remaining.