The Red Devils hope to continue to set the pace at the top of the Premier League, while Brian McDermott's men sit second from bottom and are in search of the upset.
Cummings, Morrison, Mariappa, Shorey
Robson-Kanu, Leigertwood, Tabb, McAnuff,
Roberts, Le Fondre
Rafael, Smalling, Evans, Evra
Valencia, Carrick, Cleverley
Welbeck, Van Persie, Rooney
Reading boss Brian McDermott will have the same set of players from which to choose as last time out after Jem Karacan (knee ligament) failed to overcome his injury in time for the visit of the Premier League leaders, and thus may leave Kaspars Gorkss out once more.
Chris Gunter (hamstring), Danny Guthrie (leg) and Jimmy Kebe (groin) are all expected to remain out of first-team action until the new year.
Manchester United manager Sir Alex Feguson could welcome back Antonio Valencia (hip) after the winger sat out during Manchester United's 1-0 mid-week win over West Ham. Paul Scholes is also in contention after serving a suspension in that win.
Nani (hamstring) is still sidelined with an injury alongside other long-term absentees Shinji Kagawa (knee) and Nemanja Vidic (knee); however Rio Ferdinand could return to the starting lineup after he was rested against the Hammers.
|DID YOU KNOW?|
Reading has conceded 78 percent of all its goals in the second half of games this season, which is tied for worst in the league.
The Royals have kept the joint-fewest clean sheets in the Premier League this term.
- Despite being a game behind most other sides in the league, Brian McDermott's men have allowed more shots against them than any other team.
- The newly-promoted club has conceded 23 goals this season, with only Southampton, Queens Park Rangers and Wigan letting in more.
- Manchester United has scored more headed goals than any other team in the top flight (10).
The Red Devils have drawn just one of their last 22 Premier League away ties.
Sir Alex Ferguson's side has recovered more points from losing positions than any other team in this season’s Premier League (18).
Wayne Rooney (pictured) has a joint-league-high six assists this season, tying Chelsea’s Juan Mata.
- All of United's last four league defeats on the road have been by a 1-0 scoreline.