In his first game in charge, Michael Laudrup's side delivered a virtuoso performance to put to bed any fears about the club in its second season in the top flight
With a quick tempo to the opening few minutes, it was Swansea which struck the first blow, with Michu's strike from the edge of the box finding a way past Robert Green in the opening 10 minutes for a rapid start.
QPR bossed proceedings from then on, but in what was quickly turning into a clinical display, in the second period, Nathan Dyer grabbed a goal on the break after some good work from Wayne Routledge, before Michu got another goal shortly after, with Routledge again the provider.
The game became more stretched from then on and the hosts were beginning to tire in the heat, but there was just enough time for Dyer to control an excellent Kemmy Agustien ball over the top before slotting home to make it four, while substitute Scott Sinclair made it five with a neat finish after a misplaced pass from Nedum Onuoha.
QPR manager Mark Hughes rang the change as he seeks to make his mark on the team after a busy summer off the pitch in the transfer market, with Robert Green, Fabio, Junior Hoilett and new captain Park Ji-Sung all handed their competitive first-team debuts, while Samba Diakite started in midfield having made his move from Nancy permanent in the summer.
Swansea boss Michael Laudrup handed Chico his debut at the heart of the back four alongside of Ashley Williams, after Steven Caulker returned to parent club Tottenham at the end of last season.
Elsewhere, Jonathan De Guzman came into midfield alongside Leon Britton, replacing Liverpool's new signing Joe Allen, while the exciting Michu, scorer of 16 goals in La Liga last summer with Rayo Vallecano started at the tip of a midfield trio. The surprising news of the day saw Scott Sinclair start the game on the bench.
With both sides enjoy some of the ball in the early stages, it was the visitors who struck first as early as the eighth minute, with new boy Michu putting Laudrup's side ahead.
After repelling a flowing Swansea attack, courtesy of a sliding tackle from Hill, the ball popped out on to the edge of the box to the top goalscoring midfielder in La Liga last season, who drive an effort first time with his left foot which slid underneath the body of Green, with the goalkeeper culpable.
The hosts responded well, though, and went close just moments later when Hoilett picked the ball up on the right flank and ran at Chico, twisting and turning him inside out before curling an effort just wide of the right-hand post with Vorm well beaten, while Taarabt had a few efforts blocked from distance.
A rare error from Vorm almost gifted QPR an equalizer, when after a spell of concerted pressure in the opposition's half, Fabio clipped a delightful ball over the top which Hoilett got in between Vorm and Taylor, but his diving header just fell wide, with the Dutch goalkeeper in no-man's land.
With Swansea struggling to get out of its own half, it took a lovely De Guzman free-kick from 30 yards out to force it up the pitch, which Green did well to tip round the post for a corner.
Wit Swansea providing a real threat from set-pieces, just a minute before half-time, Green had another error of judgement, refusing to come out for a ball in his six-yard box, and with the hosts struggling to get it clear, Michu struck the bar for the second time in quick succession with a toe-poked effort before it was hacked clear.
The second half began in the same vein, with end-to-end action on a hot, sunny afternoon at Loftus Road. Hoilett had a penalty claim in the opening minute of the period turned down, after he went down very easily under pressure from Rangel, while Michu's diving header at the other end went close.
But it was Swansea which got the crucial second goal, though, and that man Michu again popped up with the strike in the 53rd minute, in what was quickly turning into a dream debut for the Spaniard.
After Cisse's poor lay-off up the other end of the pitch, the visitors broke at pace, with Routledge driving at the heart of the back four before laying the ball inside the box to Michu on the run, who hit it first time, bending it brilliantly into the top left-hand corner.
With the onus now on Mark Hughes' side to come out and try and get a goal, Swansea broke on the break again, with Routledge once again setting up Dyer to coolly slot home past Green in the 61st minute after being put through one-on-one with the QPR back four all over the place.
With the heat really getting to the hosts, Swansea soon made it four, with Dyer again among the goals, after latching on to substitute Kemmy Agustien's chipped ball over the top, before bringing it down superbly and slotting it home past Green in the 71st minute.
But the away side wasn't done there and it delivered an emphatic finish to cap an astonishing game, with Sinclair, on as a sub, pouncing on yet another self-inflicted defensive error from QPR at the back to finish with an accurate left-foot finish into the far corner in the 81st minute.
With Hughes seething on the sidelines, Danny Graham went close to making it six with a deft header after a neatly worked corner, but the final whistle spared them any further embarrassment on what represented the worst possible start to the season.