Manuel Pellegrini's side lost its unblemished home record Monday and will look to avoid another damaging defeat against a team it hammered 7-0 earlier this season.
Manuel Pellegrini's high-fliers steamrollered the Canaries in the reverse fixture at the Etihad Stadium and will be seeking a quick response following Monday's 1-0 loss to title rival Chelsea.
Defeat at the hands of the Blues ended a 20-match unbeaten run for City, which had scored in its previous 61 home league games.
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Sergio Aguero has scored five goals in as many fixtures against the East Anglians but the Argentina international is unavailable with a hamstring injury sustained against Tottenham at the end of January. The onus will be on Alvaro Negredo to lead the line for City but he has scored just twice away from home in the league this season.
Fernandinho (thigh) and Samir Nasri (knee) are sidelined along with Aguero, while Javi Garcia (knock) remains doubtful.
Norwich is embroiled in a relegation battle and go into the game just two points clear of the bottom three in 15th.
Chris Hughton's side surrendered a lead when losing 2-1 to fellow struggler Cardiff City last time out but the manager remains positive as his men prepare to welcome one of the league's strongest teams.
"Manchester City can score goals at will," he told the press, "but it's a really good challenge for us. We have to put everything together and look forward to it."
Joseph Yobo, who joined on loan from Fenerbahce in the transfer window, could make his debut at center back as Ryan Bennett is doubtful with a thigh problem. Fellow defender Michael Turner (hamstring) and midfielder Jonny Howson (back) are nearing returns but will be unavailable Saturday.