Chris Hughton's side has dropped into the bottom three following two successive defeats but faces a Bluebirds team in similar trouble at Carrow Road on Saturday.
The Canaries have had a shaky start to the new campaign, winning just two of their opening eight fixtures, and now languish in the bottom three.
Their defense has also struggled of late, shipping seven goals in their previous two matches against Chelsea and Arsenal, which beat them 3-1 and 4-1 respectively in the last few weeks.
Cardiff has also lost its last two games and sits just one place and one point above the home side.
History narrowly favors the home team, with the previous 10 meetings between the two teams ending in victory for Norwich on five occasions.
This encounter will be the first time they have faced each other in the top flight, however, and Hughton will hope to welcome striker Ricky van Wolfswinkel back into the side after a foot injury ruled him out last weekend.
The 24-year-old, who joined from Sporting Lisbon in the close season, has become an integral part of the manager's plans, starting seven of the club's eight fixtures and netting against Everton in the season opener.
Hughton confirmed Van Wolfswinkel will need to undergo a late assessment ahead of the clash, though, while also revealing that fellow-striker Johan Elmander will be available after re-joining training following a thigh complaint.
Cardiff boss Mackay, on the other hand, does not have any new concerns, with long-term absentee Andreas Cornelius still out after suffering an ankle injury in preseason.