The Senegalese striker was the difference with two impressive goals and Pepe Reina's dismissal for a headbutt on James Perch made it a terrible day for Kenny Dalglish's men
A double from Papiss Demba Cisse inflicted a third straight Premier League defeat on Liverpool.
The Sengalese striker scored a fine header and then rounded the keeper to add a 2nd goal before Reina's head butt on Perch saw the visitors reduced to ten men.
The first chance of the game fell to Jonjo Shelvey whose dipping shot took a wicked deflection but just went over the bar.
A Steven Gerrard free kick then landed on the head of Martin Skrtel but he failed to find the target with a header from inside the six yard box.
Then there was controversy as Andy Carroll broke through on goal and went down ahead of a challenge by Newcastle goalkeeper Tim Krul. Replays showed that the Liverpool number nine had gone down far too easily and referee Martin Atkinson booked him for diving much to the joy of the Toon faithful.
Liverpool continued to have the best of proceedings and after a lovely ball out wide by Luis Suarez Craig Bellamy’s cross was deflected onto the bar by Krul. From the corner Danny Simpson appeared to handle on the line after Mike Williamson’s header was diverted goal bound but nothing was given despite the Merseysiders protests.
Against the run of play it was the home side who took the lead in the 19th minute. A lovely run from Hatem Ben Arfa led to him supplying a wonderful cross to the back post for Papiss Demba Cisse who guided a well angled header into the far corner with help from the woodwork.
Despite going behind the away side continued to press and were nearly level after a ball in from Bellamy fell for Carroll whose header just cleared the bar.
The Magpies were offering a threat on the break and nearly doubled their lead after a Demba Ba shot took a wicked deflection after Martin Skrtel but just went past the post.
Just before the break a Danny Guthrie cross was met by the goal scorer Cisse but this time his header didn’t find the target.
A couple of minutes after the half time interval the Geordies were extremely close to extending their lead. A floated cross in from the right by Yohan Cabaye was beautifully guided goal wards by Williamson whose header agonizingly came back out off the post.
But just before the hour mark Newcastle was to get its two goal cushion. A swift passing move ended with Ba pushing a ball across the area and after both Ben Arfa and Jamie Carragher failed to latch on the loose ball, Cisse calmly rounded Pepe Reina and found the back of the net. The Sengalese international appeared to be in an offside position but the goal stood.
Liverpool came straight back on the offensive and after Krul couldn’t deal with a cross into the box it appeared Suarez would halve the deficit. However a remarkable block from James Perch further frustrated the visitors.
Things went from bad to worse just under ten minutes from time for the visitors. After Reina recovered a Williamson header Perch intentionally tripped the Spaniard up. A headbutt from the Liverpool keeper followed with Perch making the most of it. The referee produced a red card meaning Reina will miss the reds next three games, including the Fa Cup semi final with Everton.
Newcastle then coasted to a victory which saw them move 11 points clear of the men from Merseyside.Follow GOAL.COM USA on