Jim Curtin takes charge of an MLS game for the first time following the firing of Union head coach John Hackworth.
The Revs embarrassed the U in their last meeting, on May 17. A couple of late goals masked a dominant New England performance as Philly was embarrassed 5-3 at home.
Lee Nguyen and Diego Fagundez were the stars that day, each scoring as they repeatedly tore apart the Union, and the pair have helped lead New England to a 7-5-2 record and second place in the Eastern Conference.
The Union have been better since that, with a 3-0 win over MLS' own verson of the Centralia, PA coal fire, Chivas USA, and a creditable 3-3 draw with the Vancouver Whitecaps.
Philadelphia is in eighth place in the conference, four points back of its I-95 rival, the New York Red Bulls.
Interim Union head coach Jim Curtin will be without Ethan White (R ankle sprain), while the trio of Conor Casey (low back strain), Vincent Nogueira (L groin strain) and Aaron Wheeler (R calf contusion) are listed as questionable.
New England will be without just one player, midfielder Shalrie Joseph (L calf strain).