In what was a gripping encounter in southern Italy, the home side failed to find the breakthrough despite dominance, as Edy Reja will be delighted to leave Naples with a point.Napoli's stuttering start to the Serie A campaign continued after the club was forced to settle for a 0-0 draw with Lazio at the San Paolo on Saturday.
Despite the late drama, the first half was rather forgettable, with just Hugo Campagnaro's wayward header from Ezequiel Lavezzi's acutely clipped in freekick the only chance of note, while the visiting could only muster a Hernanes shot from distance.
However, the match exploded into life after the interval, as goalkeeper Federico Marchetti eventually stole the show via a number of top-drawer saves to frustrate Napoli, which began to step up the tempo.
Lavezzi was at the forefront of the opportunities presented to the former Cagliari No.1, with a curling effort from range requiring the shot-stopper to be on his toes to dive and tip the ball away. An acrobatic attempt also surfaced from Edinson Cavani's flick, but it proved to be futile once more.
Blerim Dzemaili also got into the habit of examining Marchetti's nerve with a vicious free kick from 25 yards out, but his effort whistled just wide of the target.
An inefficient Lazio continued to go through the motions, as Djibril Cisse struggled to lead the line on the night without the assistance of the club's leading scorer Miroslav Klose, and the team could only back down to Napoli's dominance.
Mazzarri threw on Goran Pandev in a last-ditch attempt to swing the game into the hosts' favor, but Marchetti again stood firm and superbly managed to stop Lavezzi in the last kick of the game in the 94th minute, as Lazio now temporarily moves top of Serie A.
Napoli, which hosts Manchester City in the Champions League on Tuesday, is provisionally in sixth.