The Bianconeri are in pole position in Serie A and will be determined to put further distance between themselves and the chasing pack when they face the Giallorossi this weekend.
Rudi Garcia's charges opened the season with 10 successive victories to set a new Italian top-flight record from the start of a campaign, but their hosts this weekend are threatening to surpass that mark.
Since a 4-2 defeat at Fiorentina in October, Juventus has been unstoppable in the league, winning nine consecutive games and keeping clean sheets in all but one - a 4-1 triumph at Atalanta last time out.
The club's form has also seen it surge to the top of the table as it chases a third consecutive Serie A crown, and it goes into its first game since the winter break five points clear of Roma in second.
The Giallorossi do not have recent history on their side, having won just two of the last 16 fixtures between the sides.
Andrea Pirlo could be in line for a place in the matchday squad for Juve after recovering from a knee injury, though the fixture may come too soon for him, while Marco Borriello remains a doubt for Roma.
Juve will be relieved to have Carlos Tevez in contention after the Argentine was late coming back from his homeland over the new year, with reports suggesting he was caring for his pregnant wife.