In their first match at San Siro in 2014, Walter Mazzarri's men will be desperate to return to triumphant ways after back-to-back losses since the winter break.
Walter Mazzarri's side crashed out of the Coppa Italia with a 1-0 defeat at Udinese on Thursday, all but ending its hopes of winning a trophy this season.
The Nerazzurri outfit was also beaten by the same scoreline at Lazio in Serie A on Monday and has now won only two of its last eight games in all competitions, sitting sixth in Serie A. One positive to take out of Inter's cup defeat was that striker Diego Milito came through his first 90 minutes of the season after recovering from knee and thigh injuries.
Defender Hugo Campagnaro is back in contention for the team 18 points behind table-topper Juventus after serving a suspension, but in-demand midfielder Fredy Guarin is suspended. Ricky Alvarez, Esteban Cambiasso and Rodrigo Palacio are set to return to the starting lineup after dropping to the bench Thursday.
Chievo is without a win in three league matches and also exited the Coppa Italia when it was beaten 2-0 at Fiorentina on Wednesday. Eugenio Corini's side is two points above the relegation zone and was hammered 4-1 at Torino in its last Serie A away game.
Midfielder Luca Rigoni will not feature at San Siro as he serves a suspension.