Both sides have picked up momentum in recent matches and are looking good again.
Fiorentina have had a torrid start to the 2010-11 campaign and been struggling around the relegation zone. But things have taken a surge towards the better since last weekend when the Viola defeated Parma 2-0 at the Stadio Artemio Franchi.
Sinisa Mihajlovic's side are currently 15th in the table with five points from five matches and with other sides dropping points and showing bouts of inconsistency as well, the Viola are just four points off a Champions League spot.
Confronting Europe-aspiring Palermo in Florence is not going to be easy for the Viola but having won last weekend Fiorentina will be confident of garnering maximum points from this fixture.
Surging Toward The Top
After a rather modest start to the season, Palermo are back in form. A massive 3-1 win against Juventus in Turin was followed by a 2-2 draw with Lecce last weekend and on Thursday in the Europa League the Sicilians defeated Lausanne 1-0.
Palermo are 14th in the league table with five points from five matches and have started to pick up momentum. Like Fiorentina they too are just four points off a Champions League spot.
However, Delio Rossi's side have to stop conceding goals and tighten at the back as they have the joint-second worst defensive record in Serie A so far this season, having shipped in eight goals.
Jovetic, D'Agostino and Gulan are injured and will miss the visit of Palermo. Pasqual has recovered and is slated to start at left-back but winger Vargas is likely to sit out the game after leaving Friday's training session early with an injury.
Gilardino will be the lone striker up front with Cerci, Ljajic and Marchionni playing behind him in a three-man attacking midfield system.
Brichetto, Miccoli, Liverani and Rigoni are out injured for Palermo, who will once again play in a 4-3-2-1 system. Pinilla will be the lone striker upfront and Pastore and Ilicic will be deployed just behind him.