Jose Mourinho's side will aim to continue its good form at the Cornella-El Prat as it warms up ahead of next Friday's Copa del Rey final against Atletico Madrid.
Espanyol trio Cristian Alvarez, Felipe Mattioni and Simao will miss Saturday's Primera Division clash against Real Madrid.
Defender Mattioni and midfielder Simao are yet to return to training after suffering calf injuries, while goalkeeper Alvarez is out with a torn hamstring.
Madrid playmaker Mesut Ozil suffered an ankle injury in Wednesday's 6-2 win over Malaga and will miss the trip to the Cornella-El Prat. Sergio Ramos is still out with a hamstring problem, but Alvaro Arbeloa, Sami Khedira and Marcelo could all return from spells on the sidelines.
|DID YOU KNOW?|
- Espanyol is on a four-match winless run at home in La Liga (0-1-3).
- Los Periquitos are on a 10-match winless run against Real Madrid, losing eight.
- Espanyol's last home win over Real was a 2-1 triumph in October 2007.
- Real Madrid has only won two of its last five away matches in all competitions (2-2-1).
- The Castilian giant is the only team to remain unbeaten at home across all competitions in Europe's top five leagues this season (23-0-5).
- Cristiano Ronaldo (pictured, right) scored the 200th goal of his Madrid career in Los Blancos' win over Malaga. He has achieved this feat in just 197 matches.