The Dutchman has netted in his club's last five games in the competition, a streak that includes the 2-1 win over Borussia Dortmund in the 2012-13 final at Wembley in May.
Only three players in the history of Europe's premier club competition have scored in six successive fixtures and Robben will aim to join Marouane Chamakh, Burak Yilmaz and Cristiano Ronaldo in achieving the feat.
The reigning champion will enter its Group D home game against the Czechs as a heavy favorite after a superb start to the season.
Bayern tops the Bundesliga with seven victories from nine matches and has easily won both of its Champions League fixtures, proving particularly impressive in a 3-1 win at Manchester City earlier this month.
The Bavarian giant has scored in its last 31 games and survived a scare to defeat Mainz 4-1 on Saturday.
Bayern's 33-match unbeaten streak in the Bundesliga came under threat when Shawn Parker's goal helped Mainz to the lead at the break.
However, Mario Gotze came on at halftime and helped to change the match, as two goals from Thomas Muller and additional strikes from Robben and Mario Mandzukic carried Pep Guardiola's side to victory.
Winger Franck Ribery was rested as a precaution, but the Frenchman is likely to be fit for Wednesday's clash.
"It's nothing serious. I wanted to play, but the doctor said it was too much of a risk," the winger said.
Brazil defender Dante was substituted in the win over Mainz with an ankle injury and will be out at least a fortnight. Thiago Alcantara also has an ankle problem and is unavailable together with fellow midfielder Xherdan Shaqiri (hamstring).
Defender Jerome Boateng is suspended following his red card in Manchester and although midfielder Javi Martinez has returned to training following groin surgery, Wednesday's match will come too soon for him.
Viktoria Plzen sits second in the Czech top flight, six points behind Sparta Prague but undefeated in its 11 league matches this season.
Plzen has lost each of its Champions League fixtures, succumbing to a 3-0 home defeat against Manchester City before CSKA Moscow beat the club 3-2 earlier this month.
Center back Marian Cisovsky missed both of those defeats due to a calf injury but returned in Saturday's 1-1 draw with Sparta Prague.
Cisovsky was the equal top-scorer in Champions League qualification, netting five goals.
David Limbersky, another member of Plzen’s defense, has not played in almost a month due to a thigh injury and is set to miss out again.
MasterCard is excited to present episode one of the Priceless Memories UEFA Champions League video series. See what Liverpool legend Didi Hamann has to say about the infamous 2005 final!