The Germany international claimed his second goal of the Bundesliga season to help Dortmund maintain their perfect start to the new league campaign by demolishing Thorsten Fink's men at Signal Iduna Park.
But the coach was particularly impressed by the "crazy" ingenuity Reus showed by leaving the ball for Robert Lewandowski to make it 4-2.
"I've told Marco that he has earned a place in heaven for that," Klopp told Sky.
"I've never seen anything like it. Usually, when the ball comes like that, you give it all you've got to blast it in, yet he just let it through to Lewandowski. It's crazy."
Reus himself was thrilled with the way his team kept going despite initially surrendering a two-goal lead.
The 24-year-old believes he has rediscovered his best form, and is eagerly anticipating the Champions League fixture with Napoli at the Stadio San Paolo on Wednesday.
"We didn't give up at 2-2 and demanded more of ourselves, now we focus on the Champions League," he told the official Bundesliga website.
"More intensity like that over a full 90 minutes and we'll be difficult to beat. I've got my rhythm and confidence back. All I care about is football, I love it, and I love this team. Now onto Napoli."