The striker made his comeback against England following surgery on his knee and the produced a devastating display, neting two goals to all but knock out Roy Hodgson's men with one game still to play.
There wasn't much joy for the other Premier League representatives though, as a Cote D'Ivoire team boasting three England-based players fell to their first defeat of the tournament at the hands of a Colombia side starring a West Ham loanee...
After so much attention was given to his fitness before the match, it was almost inevitable that the Liverpool forward would make his mark on Uruguay’s decisive Group D match with England.
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And the 27-year-old cropped up with two priceless goals that looked to have sent his club captain Steven Gerrard and his international team-mates tumbling out of the World Cup at the first hurdle.
Suarez first struck just before the break when he got on the end of a chipped Edinson Cavani cross to direct a header beyond an outstretched Joe Hart.
He looked to be tiring in the second half as his lack of match fitness began to show, but he was still quickest to react to Gerrard’s misguided header, latching onto the loose ball and smashing it high into the roof of Hart’s goal.
The forward was congratulated by team-mates as he came off with just minutes remaining and will surely play a key role if the South Americans are to qualify for the knockout stages.
One of the top performers in the Premier League last year as Manchester City won the title, Yaya Toure has found it difficult to transfer that form to the World Cup and he failed to shine yet again as Cote D’Ivoire fell to defeat against Colombia.
The playmaker wasn’t his imposing self against the South Americans and never got the space to run with the ball at his feet, a sight that struck fear into Premier League defenders throughout last season.
The 31-year-old went close with a free kick but failed to trouble the goalkeeper as his side slumped to their first defeat of the tournament, leaving them in need of a result against Greece to qualify for the last 16.
The Newcastle midfielder was in his usual bullish form, trying to dictate the play for Cote D’Ivoire using his strength in the middle of the park, but he failed to tame a ferocious Colombian counterattack which caused the African side difficulties.
Finding his side behind late on, Chiekh Tiote let his frustrations get the better of him as he picked up a booking for a clumsy foul.
The Swansea City man made a terrific start to his World Cup when he grabbed the equaliser against Japan, but he struggled to replicate that form against a staunch Colombian defence.
The Cote D’Ivoire striker failed to make an impact as his side slumped to defeat, almost injuring himself in a wayward attempt at a bicycle kick, before he came off to make way for former Chelsea star Didier Drogba.
The full-back, who spent last season on loan at West Ham, was on the winning side once again as Colombia held of a late fight-back to beat Cote D’Ivoire 2-1
After finding the net in his side’s opener, the defender was a little less adventurous this time out, pre-occupied by a quick African side which boasted the pace of former Arsenal winger Gervinho and ex-Leeds man Max Gradel.
The 27-year-old’s busy afternoon came to an end in the 79th minute when he was replaced by Santiago Arias after another solid outing.