The Gunner's title hopes were dealt a hefty blow on Saturday as the Premier League leaders were outclassed by a rampant City in an enthralling game at the Etihad Stadium.
|7/2||Arsenal are 7/2 with Bet Victor to win the Premier League this season|
Wenger admitted that Arsenal did not deserve anything from a game in which the north London club were comfortably second best.
"It hurts to lose like that, but we made too many mistakes in the middle of the park," Wenger said.
"Overall they deserved the win, we have to go home and recover, we made too many technical mistakes."
The Frenchman - who lost defender Laurent Koscielny due to a cut on his right knee late in the first half - felt that fatigue may have played a part in his side's display following their exertions in the Champions League in midweek. Arsenal lost 2-0 at Napoli on Wednesday, but still progressed into the knockout stages.
"It's always difficult to know," he added. "Our schedule was not ideal. Is that the only explanation? I am not sure.
"There is nothing worse in football than being tired and running after the score.
"We want to win. We are very sad because we lost a big game. We know a big season depends on winning big games."