Having managed city rivals Everton and the Reds' arch-enemies, the Scot knows that he will not be a popular man inside the stadium but is relishing the occasion.
United won on their last visit and completed the double over Brendan Rodgers's side later in the season while Moyes has never won at Anfield, only tasting victory on three occasions against Liverpool, but he is confident of turning that record around.
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"It has always been a difficult place to go but I am looking forward to going back there."
Moyes also refused to guarantee any new arrivals at Old Trafford ahead of the deadline despite his pursuit of moves for Marouane Fellaini, Leighton Baines, Ander Herrera and Daniele De Rossi.
"I don't know how busy it's going to be but it's a busy football market," he added. "It might be busy in the next few days and I hope we do a little bit of business but I couldn't guarantee that.
"I wouldn't disclose any names, just let the clubs deal with it and we'll try and do it on a professional manner."