Kenny Dalglish makes one change following his side's 3-0 in against Everton in the Merseyside derby on Tuesday, as Maxi comes in for HendersonSteven Gerrard, Andy Carroll and Luis Suarez have retained their places for Liverpool's FA Cup sixth-round tie against Stoke City at Anfield.
Gerrard continues in central midfield following his hat-trick against Everton as Kenny Dalglish makes one change from the side which started in the Merseyside derby on Tuesday.
Jordan Henderson drops to the bench as Maxi Rodriguez starts on the right flank.
For Stoke City, Tony Pulis makes four changes from the side that lost 1-0 against Chelsea at Stamford Bridge last Saturday.
Asmir Begovic loses his place in goal to Thomas Sorensen, while in midfield Matthew Etherington returns on the left flank at the expense of Ricardo Fuller.
Glenn Whelan is preferred to Salif Diao in central midfield, while in attack, Jonathan Walters keeps his place but Kenwyne Jones drops to the bench as Peter Crouch comes in.
Liverpool: Reina; Kelly, Carragher, Skrtel, Enrique; Maxi, Gerrard, Spearing, Downing; Suarez, Carroll.
Subs: Doni, Coates, Kuyt, Adam, Henderson, Flanagan, Shelvey.
Stoke City: Sorensen; Wilkinson, Shawcross, Huth, Wilson; Shotton, Whitehead, Whelan, Etherington; Walters, Crouch.
Subs: Nash, Delap, Jerome, Upson, Pennant, Jones, Palacios.