The championship hosts will be without one of their key players when they face the Super Eagles in the Caf organised competition
South Africa will be without their key midfielder Reneilwe Letsholonyane when the African Nations Championship gets underway in the country in January.
The Kaizer Chiefs player was withdrawn from the squad following a knee injury.
The 31-year-old was last Monday included in the squad that will do duty at the 2014 edition of the tournament in January, but will now miss the event because of the injury.
A statement on the SAFA website announced that Moroka Swallows midfielder Asavela Mbekile has been called up as a replacement for the injured AmaKhosi star.
South Africa will play the Super Eagles of Nigeria in Group A of the CHAN competition in Cape Town on January 19.