The Seattle Sounders striker will return to Craven Cottage in January after agreeing a temporary move back to his former side ahead of the World Cup
Dempsey spent five years at Fulham between 2007 and 2012 before joining Tottenham for a one-year spell.
Fulham head coach Rene Meulensteen stated on Friday that the United States captain is set to join after completing medical checks.
"[Meulensteen] confirms Clint Dempsey has undergone a medical at the club with a view to returning to Fulham," the club stated via their official Twitter account.
"Dempsey would return for January and February if a loan deal is completed."
Meulensteen added to reporters: "Clint will be a boost for us."
The 30-year-old has scored 50 Premier League goals for Fulham, more than any other player.