Steven Pienaar will be involved in the FA Cup fifth round this weekend when Everton welcome Swansea City at Goodison Park.
The Toffees will be looking to put their last weekend's defeat to Tottenham behind them, and Pienaar in particular, will be hoping to play the entire 90 minutes.
In the Championship, AFC Bournemouth will play host to Burnley on Saturday afternoon where midfielder Andrew Surman is expected to be in the starting line-up.
Tokelo Rantie has been used mainly as a sub in recent weeks, but the former Pirates marksman will be pleased with some game time despite struggling with form at times.
Doncaster Rovers will entertain Barnsley and going by recent performances, then Bongani Khumalo should start in the heart of that Rovers defence once again.
The 26-year-old centre-back has been one of the most consistent players in the Rovers defence since joining them from Tottenham Hotspur earlier this season.
Dean Furman will be hoping to return to the starting eleven on a permanent basis this weekend after changing the complexion of the game last week.
Kgosi Ntlhe's Peterborough United will play at home against Walsall on Friday, although it is unclear whether the young South African full-back is ready to return into the team having missed last weekend's 2-1 victory at Leyton Orient.
South African goalkeeper Darren Keet will begin his weekend with KV Kortrijk away to Club Brugge on Friday night.
Brugge are highly motivated going into this encounter following their last weekend's 3-1 victory over Racing Genk while Kortrijk were held to a 2-2 draw at home by Anderlecht, but Keet will be hoping for a cleansheet this time around.
Ayanda Patosi's KSC Lokeren visit KAA Gent on Saturday afternoon, and the South African midfielder is expected to once again start on the bench.
Patosi has struggled to reclaim his place in the starting line-up, but the 21-year-old player always gives his best whenever given the opportunity.
Having impressed in his first two official games for KV Oostende, Andile Jali will be hoping for a start when his new side face KV Mechelen at the Argosstadion Achter de Kazeme on Saturday.
Jali has settled in quickly in the Jupiler League, and this should be the beginning of greater things for the 23-year-old Eastern Cape-born midfielder.
Anele Ngcongca will lead his side, Racing Genk as they come up against Lierse SK on Saturday night.
The South African national team right back has been enjoying his new role in the team, and he is expected to put in another great performance this weekend.
Kamohelo Mokotjo's PEC Zwolle will look to build from their last week's 1-1 draw against champions Ajax Amsterdam when they visit Cambuur Leeurwarden on Sunday.
Mokotjo missed out on the opportunity to face his Bafana teammate Thulani Serero on the day, but he will be itching to return to full fitness this weekend.
Serero's Amsterdam will be at home against Heerenveen on Sunday afternoon, and the attacking midfielder will be looking to help his side claim all three points and extend the lead at the top of the Dutch League.
Serero has just been named in the Bafana squad to face Brazil on March 5, and the Gauteng-born former Ajax Cape Town player will be aiming to justify his selection by doing his best against Leeurwarden.
Daylon Classen's Lech Poznan will be in action against Slask Wrakow on Monday evening, where the Bafana midfielder will be hoping to impress and attract interest from bigger leagues around Europe.
Claassen hasn't been in the spotlight since leaving the Belgian Pro League, but he also hasn't stopped working hard.
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