The former goalkeeper believes the Catalan side have more than enough to replace the prolific attacker and has insisted they know what to expect against Celtic
The Argentina international picked up a hamstring injury in Barca's 2-0 La Liga win over Almeria at the weekend and will consequently be out of action for two to three weeks.
But Zubizarreta has backed Gerardo Martino's squad to step up in the 26-year-old's absence, telling reporters: "Playing without the best player in the world isn’t what you want, but these things happen. We have a great squad and we will be using that."
The former Spain goalkeeper then went on to discuss Tuesday's Champions League encounter against Celtic and insisted that the Blaugrana are prepared for the atmosphere at Celtic Park following their shock 2-1 defeat there last season.
"We know what to expect at Celtic Park. We know what the atmosphere will be like. Celtic are a team that are very clear about how they play," he added.
Tuesday's match is scheduled to kick off at 20:45CET.