The Portugal international is open to an Old Trafford exit with the Red Devils willing to listen to offers for the out-of-favour winger before the transfer window closes on Friday
Inter have approached Manchester United over a deal to take Nani on loan for the rest of the 2013-14 campaign, Goal understands.
The out-of-favour winger has consistently been linked with an Old Trafford exit and has only made 10 senior first-team appearances this season under new manager David Moyes.
Goal reported on January 15 that the Red Devils would be open to offers for the Portugal international, with Juventus having initially expressed an interest before backing out after discovering the player's salary demands.
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Injuries and a lack of form have not helped Nani, however, while the January club-record signing of Juan Mata from Chelsea will do little to increase his chances of more regular playing time.
The winger is desperate to find a solution in a World Cup year, with Portugal having reached the Brazil showpiece after progressing past Sweden in a play-off back in November.
United, for their part, would consider a loan bid from Inter before the window shuts on Friday, with the Serie A club looking to get their season back on track having failed to win a match since the Milan derby on December 22.
New president Erick Thohir is ready to assist Walter Mazzarri by providing funding for transfers, with Juventus forward Mirko Vucinic a potential arrival despite negotiations for a swap deal involving Fredy Guarin breaking down.