The Argentinian believes the clash at the Stadium of Light on Sunday is worth much more than just three points to the Saints, who are not yet mathematically safe
Despite a bright start to his managerial career at Southampton, one which included a 3-1 home victory against reigning champions Manchester City, Pochettino's side have since struggled for consistency, failing to win vital games against QPR, Newcastle or Wigan yet picking up surprising home results against Liverpool and Chelsea respectively.
Furthermore, the Saints find themselves without a win in their last four games and, were it not for the inconsistency of those around them, may have been in a far more vulnerable state.
However, as his squad prepares to travel to the Stadium of Light for this Sunday's vital clash Pochettino remains certain that his squad can pull off a victory against Paolo Di Canio's men and ease the pressure on themselves.
"It is clear that we welcome any losses of rival teams that are in similar positions to ours," the Argentinian said. "We're always keeping an eye on those sort of games.
"We know that we have two games left; we need to do our job and get the maximum number of points from these last two games.
The Argentinian went on to acknowledge the pressure facing his squad, but insisted that, as long as his team kept their focus, that the goals would come.
He added: "We are very aware that the game on Sunday is going to be quite intense and that both teams are going to be playing for more than just the three points.
"We know that the atmosphere is going to be very much charged. We're going to face a side that has been physical ever since the arrival of Paolo di Canio so we are prepared to compete on Sunday.
"Recently, we have had trouble basically finding the back of the net. We need to be confident that in the next game we will be able to score because goals are what actually get you results so we need to keep the focus."
Southampton go into the clash on 39 points, one above their opposition and four above Wigan, who currently occupy the last relegation position.