The 48-year-old says the Royals should follow the example of the Cottagers who have established themselves in the Premier League ever since their promotion way back in 2001
The Cottagers have enjoyed 11 straight seasons in the top flight ever since their promotion from the Championship in 2001, finishing mid-table in most of those campaigns and even enjoying two Europa League adventures.
Reading, meanwhile, have dropped straight back to the second tier after a solitary season in the Premier League but Adkins remains positive and hopes to replicate the success of their opponents this Saturday.
"We're not an established Premier League club. We've been in the division and the challenge now is to get back there and have a period of sustainability," Adkins told reporters.
"From that the target would then be to become an established Premier League club. Fulham have managed that and I'd put West Brom and Stoke in the same bracket.
"There might be a situation where you yo-yo a bit between the divisions, that's just being realistic.
"But the structure has to be right and I definitely believe we're on the right lines for that."
Adkins guided Southampton to back-to-back promotions from League One and is adamant he has what it takes to bring Reading straight back up.
"Having been promoted with Southampton, I know what it takes to go Saturday-Tuesday-Saturday-Tuesday," he added.
"You must have a squad of players who can deal with the injuries and suspensions that come along.
"And when you do get promoted again you have to be able to sustain being in the Premier League and not make dramatic changes. You have to build gradually."