The 28-year-old had initially ruled himself out of the tournament due to fears over his safety and an ongoing row over player bonuses with the Togolese FA.
But talks between Adebayor and the country's president, Faure Gnassingbe, have prompted a turnaround from the Spurs striker.
Adebayor’s u-turn leaves the north London club desperately short of options up front, with Jermain Defoe their only recognised striker, though they are expected to make a move to sign Leandro Damiao from Internacional.
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Spurs manager Andre Villas-Boas had publically stated that he would not block Adebayor from taking part in the tournament, but the striker hinted at a disagreement with the Portuguese boss over his eventual decision to travel.
“Yes, this is normal. In a club there is the coach, the fans and the president,” Adebayor told the Togolese Football Federation's official website when asked about Villas-Boas.
“So that’s what he told the press, but this is not what he told me. There is a difference between what is said face to face and what is said to the press.
“So I will go there and I will discuss it with Daniel Levy after I get back. No worries.”
Adebayor was on board the Togo team bus when it was attacked in Angola in 2010, an incident which cost three people their lives.