The defender signed a five year contract on Wednesday and will undergo a medical on Thursday morning before his unveiling
The defender, who was part of the Germany team which won the World Cup this summer, signed the five year deal on Wednesday and will undergo a medical on Thursday morning before being presented to the media.
A statement on the Spanish club's website read: "Valencia CF have reached an agreement with Sampdoria for the transfer of German international centre-back Shkodran Mustafi.
"The player signed a contract on Wednesday to become a Valencia player until June 30, 2019.
"Mustafi, 22 and a champion with Germany in the World Cup in Brazil, will complete a medical review on Thursday at 9.45 am. Then, at 10.00, the player will be presented to the media."