The Netherlands international, capped once, has opted to ink a deal with the Russian outfit as he aims to relaunch his career after being released by Real Madrid
The Netherlands international had been without a club ever since leaving Everton last summer after an unsuccessful one-year loan spell, and will now be looking to get his career back on track at the Russian outfit.
Drenthe, 25, has signed a contract with Alania until the summer of 2016.
"We hope that he will become one of the team's leaders. We did not only bring him in for his fine technique and pace, but also because of his personality," head coach Valery Gazzaev said, commenting on the move.
The left-footed winger came through the ranks of the Feyenoord youth academy, and joined Real Madrid in the summer of 2007 after impressing at the European Under-21 Championship.
He has since had temporary loan spells with Hercules and Everton.