Widely expected to beat Ukraine in the first leg of their European qualifying play-off for next year's World Cup, France fell to a shock 2-0 loss to leave themselves with an uphill task.
Second-half goals from Roman Zozulia and Andriy Yarmolenko put Mikhail Fomenko's side in control of their own fate in the Olympic Stadium in Kiev, putting Didier Deschamps' men in danger of missing out on the World Cup for the first time in 20 years.
Ukraine, who have lost their previous three qualifying play-offs, now have real hope of booking their tickets to Brazil after an eighth clean sheet and 11th unbeaten game under Fomenko.
A majority 55.4% of Goal Singapore readers believe that the French will not be able to overturn the deficit in the return leg in Paris, which is due to be played on Wednesday morning Singapore time.
This is despite the firepower of Karim Benzema and Franck Ribery, the latter having been tipped as a serious contender for the Fifa Ballon d'Or. The hosts will also miss centre-back Laurent Koscielny, who was sent off deep in stoppage time.
The other ties see Portugal take on Sweden with a 1-0 lead from the first leg, while Greece lead Romania 3-1 and Iceland held Croatia 0-0.