The Lazio goalkeeper has not been involved in the Azzurri set-up since 2010, but has been in fine form this season which has earned himself a spot in the team.
There are six Juventus players named by Prandelli, while AC Milan have five stars involved in the squad, including new €22 million [£19m] signing Mario Balotelli.
Only three Italians who play outside the country have been chosen for the team to face the Dutch: Newcastle United full-back Davide Santon and Paris Saint-Germain pair Salvatore Sirigu and Marco Verratti.
The international friendly, which kicks off at 20:30CET on Wednesday night in Amsterdam, will not feature Leonardo Bonucci, as the Bianconeri defender was dropped over his ban for insulting an official in Serie A.
The likes of Giorgio Chiellini, Christian Maggio and Federico Balzaretti have missed out on the squad due to injury.
The squad in full to face Netherlands:
| Name | Club |
| Goalkeepers: | |
| Gianluigi Buffon | Juventus |
| Morgan De Sanctis | Napoli |
| Federico Marchetti | Lazio |
| Salvatore Sirigu | Paris Saint-Germain |
| Defenders: | |
| Ignazio Abate | AC Milan |
| Davide Astori | Cagliari |
| Andrea Barzagli | Juventus |
| Daniele Gastaldello | Sampdoria |
| Federico Peluso | Juventus |
| Andrea Ranocchia | Inter |
| Davide Santon | Newcastle United |
| Midfielders | |
| Antonio Candreva | Lazio |
| Daniele De Rossi | Roma |
| Alessandro Diamanti | Bologna |
| Alessandro Florenzi | Roma |
| Emanuele Giaccherini | Juventus |
| Riccardo Montolivo | AC Milan |
| Antonio Nocerino | AC Milan |
| Andrea Pirlo | Juventus |
| Marco Verratti | Paris Saint-Germain |
| Attackers: | |
| Mario Balotelli | AC Milan |
| Stephan El Shaarawy | AC Milan |
| Alberto Gilardino | Bologna |
| Sebastian Giovinco | Juventus |
| Pablo Osvaldo | Roma |