Nigel Adkin's struggling Saints host Chris Hughton's men at St Mary's on Wednesday November 28 - and you can be there to watch it in person
To be in with a chance of winning the tickets, simply send your answer to the following question along with your name, address and telephone number to email@example.com.
Which team beat Southampton to the Championship title last season?
The competition will close at 13.00GMT on Friday, November 23, and winners will be announced later in the day, but don't worry if you're not successful - you can always win a pair of tickets by visiting your nearest Barclays ATM and requesting a receipt or by going online to www.barclaysticketoffice.com – you don't even have to be a Barclays customer.
Match tickets are up for grabs EVERY 90 minutes, every day, throughout the 2012-13 season.
Further information and terms and conditions are available from www.barclaysticketoffice.com.