Having seen off Everton in the previous round, the west Yorkshire side host the south coast club looking to capitalise on the Saints' leaky defence to advance to the fifth round
Peltier, Lees, Pearce, Pugh
Norris, Austin, Tonge, White
Yoshida, Hooiveld, Seaborne, Reeves
Ward-Prowse, Schneiderlin, Chaplow
Do Prado, Mayuka, Rodriguez
Leeds welcomed back three senior players from injury lay-offs in Saturday's 1-0 defeat to Birmingham City, including skipper Lee Peltier.
Rudy Austin and Michael Tonge joined their captain in returning to Neil Warnock's starting line-up and will be in contention.
Ross McCormack (ankle) is still unavailable and Ryan Hall, on loan from Southend, will miss out after appearing for his parent club in the competition earlier in the season.
Nigel Adkins is without record signing Gaston Ramirez (bruised thigh), who remains sidelined until mid-November, while Jack Cork (knee) is unlikely to be risked.
Frazer Richardson (thigh) is also unavailable for selection against his former club, having not played since picking up a knock in the Saints’ 2-2 draw with Fulham on October 8.
|DID YOU KNOW?|
- Southampton's 26 goals conceded in their first nine Premier League games since promotion is a league record. Leeds are 10/3 with Bet365 to score over 2.5 goals in this game.
- The last time that Leeds United travelled to St Mary's was on the opening day of last season. The Saints' 3-1 victory formed part of their longest-ever winning run of league games (10).
- After Chelsea, Manchester United and Manchester City, Southampton's transfer outlay represented the fourth highest net spend in the country across the summer 2012 transfer window, bringing in the likes of Gaston Ramirez and Emmanuel Mayuka (pictured right).
- Leeds are one of only three lower division clubs to have knocked a Premier League club out of the Capital One Cup so far this year, having defeated Everton in the previous round.
- Of their six away fixtures so far this season, Warnock's men have won two, drawn two, and lost two, scoring 10 goals and conceding 10.
- When Southampton and Leeds last met in the Premier League in January 2004, the two clubs had gone a combined 41 years in the top flight without being relegated.