Called into action twice in the first half, palming a Lallana volley over the bar and tipping wide from Rodriguez. Saved from Lallana again after the break but was rarely tested.
Found it easier to trouble Southampton going forward as Steven Davis moved to right-back following an injury to Luke Shaw forced a reshuffle.
Ended an excellent week, having scored for Germany against England at Wembley, by playing his part in ensuring Arsenal picked up a clean sheet. Had his shirt pulled by Fonte as the Gunners were awarded a penalty which Giroud converted.
Could not provide an attacking threat but was assured in defence and allowed Shaw and Clyne no space to trouble the Arsenal right-hand side.
Put his red card for France behind him to turn in the sort of reliable performance fans now expect of the centre-back. Produced one excellent tackle to deny Rodriguez a chance at goal.
The deepest of the Arsenal midfielders stuck to his usual disciplined task in the absence of the suspended Mathieu Flamini. Forced off with a knock late in the second half.
Struck the post with a sensational back heel to nearly complete an excellent team move which would have put Arsenal in front. Evidently playing with confidence after an excellent start to the season.
Provided a cross for Ramsey to hit the post and drifted from left to right throughout, constantly looking to link up with the Welshman, Cazorla, Wilshere and Giroud. Substituted for Nacho Monreal.
Came to life in bursts, at one point wriggling away from Schneiderlin and Wanyama brilliantly. Replaced by Theo Walcott with 20 minutes remaining after a strong showing.
Back in the Arsenal starting XI, the midfielder was inches away from giving his side the lead with a clever lob which hit the post. Saw a header saved by Boruc and turned in an accomplished performance for a player who has come in for criticism in recent weeks.
Gifted the opener by Boruc's haphazard attempts to turn away from him. Displayed his usual mixture of strength and composure, entering into a physical battle with Fonte and Lovren. Sent Boruc the wrong way with a late penalty to seal the win.
Allowed Arsenal a cheap opening goal with a farcical attempt to beat Giroud with some ill-conceived skill. Pressured by Arsenal fans every time he received the ball from then on. Could do little about Giroud's well-placed penalty.
A decent defensive performance from the left-back, but rarely ventured forward and was forced off at half-time after picking up an injury.
Gave away a clear penalty, pulling Mertesacker's shirt to allow Arsenal to score a second when his side was chasing an equaliser.
Booked for a high challenge on Giroud at the end of the first half and was given a difficult afternoon by the physical French striker.
Could only watch as Boruc made a meal of his pass and allowed Giroud to score. Moved to left-back following an injury to Shaw and got forward but could not provide any real danger.
Had Southampton's best chance of the first half, but saw his strike comfortably saved by Szczesny. Shot straight at the Pole after the break before being replaced by Dani Osvaldo.
Offered decent delivery from dead ball situations but saw little return for his efforts throughout the game. Unable to truly have an impact on the afternoon.
Asserted himself early on, shrugging off the likes of Giroud and Wilshere with robust work in midfield but was booked shortly after the interval. Hammered a volley over the bar as the visitors searched for an equaliser.
A tidy and confident performance in amongst Arsenal's vibrant midfield. Broke up attacks but could not launch many threatening moves for his side.
Displayed skill on occasion in the first half and saw an improvised volley saved by Szczesny but was largely unable to get beyond the Arsenal back four.
Had a quiet first half and moved to a slightly deeper position after the introduction of a striker partner in Osvaldo. Had little in the way of genuine chances throughout the game.
Came on at half-time in place of the injured Shaw and moved into an unfamiliar position at right-back. Struggled at times with Gibbs and Cazorla.
Brought on as Southampton chased an equaliser. Drove through Wilshere and Mertesacker but produced a tame shot and was otherwise quiet.