Atlanta United extinguished the Chicago Fire in a 4-0 demolition, while Minnesota United earned its first MLS point.
Venezuelan star Josef Martinez was at the double as expansion franchise Atlanta produced a ruthless display to make it back-to-back wins against 10-man Chicago on Saturday.
Atlanta embarrassed Minnesota 6-1 last week and Gerardo Martino's men were at it again in front of a sell-out crowd, with an own goal and Hector Villalba inspiring the hosts.
Brandon Vincent turned the ball into his own net in the fourth minute as Atlanta's high octane style of play forced an error and it got better for the home side seven minutes later when Johan Kappelhof saw red for bringing down Martinez.
Atlanta made the numerical advantage count in the second half as Martinez - the hat-trick hero from last week - sprung the offside trap and rounded goalkeeper Jorge Bava on the hour-mark.
Villalba made it 3-0 in the 67th minute before Martinez completed his brace eight minutes from time as Atlanta took its season tally to 11 goals to become just the second MLS team to manage that total in three matches.
Minnesota had something to celebrate after claiming its first point as an MLS team in a 2-2 draw against the Colorado Rapids.
The visitors came from behind and took the lead before the hour-mark thanks to Kevin Molino and Christina Ramirez, but Colorado was not to be denied by Minnesota, which had Justin Davis sent off in the 70th minute, as Marlon Hairston ensured a share of the spoils for the Rapids.
After consecutive losses to open the season, the LA Galaxy overcame Real Salt Lake 2-1 and Maximiliano Urutti's brace saw FC Dallas defeated the New England Revolution by the same scoreline.
Cyle Larin scored twice in Orlando City's 2-1 win at home again the Philadelphia Union, Sporting Kansas City was a 2-1 victor against the San Jose Earthquakes, New York City was held to a 1-1 draw by the Montreal Impact, Toronto FC topped the Vancouver Whitecaps 2-0, D.C. United lost 2-0 to the Columbus Crew and the Portland Timbers preserved their 100 percent record with a 4-2 win against the Houston Dynamo.