The Bluerchati will travel to the Turin-based club on Sunday hoping to put a dent in the impressive form that the reigning Serie A champions have forged this season
Many sides opt to man-mark the veteran Italy international such is his talent on the ball, to varying degrees of success.
However, the midfielder is just one of a host of concerns for the Bluerchati boss, who believes his side have a chance of beating the Bianconeri but says it will not be remotely easy.
“I'm not a technician who likes to match up with the opponent’s formation,” he told a press conference.
“They are a very strong side, but we believe we can win.
“We will not focus purely on Andrea Pirlo - he is a special player, but there are others who can cause us problems.”
Sampdoria sit 15th in Serie A after 18 games in the 2012-13 campaign, just two points above the relegation zone.
Antonio Conte’s men, on the other hand, are seven points clear at the top of the table on 44 points and are in a solid position to retain the Scudetto.