Eren Derdiyok bagged a hat-trick while Stephan Lichtsteiner and Admir Mehmedi also got their names on the scoresheet at St Jakob Park.
Mats Hummels, Andre Schurrle and Marco Reus struck for the Germans, but it was not to be for Joachim Low's men, and Podolski stated the team are now focusing on their next match.
"We have to be ready to take some criticism in the next days. That is normal after such a game. But our plan is to be fit for the first match, that is our way," he told Goal.com after the defeat.
"Sure, such a loss hurts but we go forward. Switzerland have played very well and we’re not yet where we want to be. We’ve got a lot of work to do."
Germany play their final warm-up fixture versus Israel in five days time in Leipzig.