Fernando Torres - who has scored four in his last four games against the Villans - and Kevin De Bruyne miss out, while Ciaran Clark comes in for Nathan Baker for the visitors
Kevin De Bruyne drops to the bench, but Fernando Torres misses out out on the 18-man squad altogether due to injury.
Villa, who lost the same fixture 8-0 last December, make just one change from the side who came from behind to beat Arsenal 3-1 at the Emirates Stadium on Saturday, with Ciaran Clark coming in for Nathan Baker
New signing Antonio Luna retains his starting spot, with fellow summer recruits Leandro Bacuna, Nicklas Helenius, Jores Okore, Jed Steer and Aleksandar Tonev all looking for their competitive bow from the bench.
Chelsea starting XI: Cech; Ivanovic, Cahill, Terry, Cole; Ramires, Lampard; Mata, Oscar, Hazard; Ba
Subs: Schwarzer, Azpilicueta, Mikel, De Bruyne, Van Ginkel, Schurrle, Lukaku
Aston Villa starting XI: Guzan; Lowton, Vlaar, Clark, Luna, El Ahmadi, Westwood, Delph, Agbonlahor, Weimann, Benteke.
Subs: Steer, Bennett, Okore, Bacuna, Sylla, Tonev, Helenius